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butabarbital will lower the level or impact of doxorubicin liposomal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.butabarbital will reduce the level or impact of sufentanil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.butabarbital will decrease the extent or impact of levok